PPI’s & Iron Deficiency

“Iron Deficient?

Have GERD or frequent Indigestion?”

Then you’re probably taking a Proton Pump Inhibitor (PPI) like Prilosec, Prevacid, Dexilent, Aciphex, or Protonix.  If so, you should be taking Proferrin® because PPI’s can and do impair absorption of non-heme iron. Your “typical” iron supplement won’t help if you’re taking a PPI,  according to Dr. Sharma (gastroenterologist).1

“These cases presented suggest that omeprazole-induced achlorhydria may impair the response to oral iron therapy”1  

“A hypochlorhydric state, therefore, would impair predominantly, the absorption of non-heme iron.”1   

If you are taking a PPI, Proferrin® heme iron is your best choice by far.

Why you should choose Proferrin® brand Heme Iron Polypeptide (HIP):

  • The ONLY Heme iron sourced from USDA edible red blood cells
  • Lowest cost per mg of Fe (as HIP) in the U.S. market
  • Multiple published “peer reviewed” medical studies using Proferrin® 2,3,4,5
  • Maintains healthy iron levels 3,4,5

Visit Proferrin.com to buy Proferrin® or to learn more about the Proferrin® brand and the science behind our products.


  1. Tempel, Mila et al. “Effects of omeprazole on iron absorption: preliminary study.” Turkish journal of haematology : official journal of Turkish Society of Haematology vol. 30,3 (2013): 307-10. doi:10.4274/tjh.2013.0042
  2. Seligman, PA, Moore, GM, Schleicher, RB. Clinical studies of hip: An oral heme-iron product. Nutrition Research. 2000;20(9):1279-1286. doi:10.1016/S0271-5317(00)00215-3.
  3. Nissenson, AR, Berns, JS, Sakiewicz, P, et al. Clinical evaluation of heme iron polypeptide: sustaining a response to rHuEPO in hemodialysis patients. American Journal of Kidney Diseases. 2003;42(2):325-330. doi:10.1016/S0272-6386(03)00658-9.
  4. Ndegwa, Sarah, and Raymond Banks. “Heme Iron Polypeptide (Proferrin®) versus Oral and Injectable Iron Products for the Treatment of Anemia.” Cadtha.ca, 28 Sept. 2007.
  5. Abdelazim IA, Abu-Faza M, Elbiaa AA, Othman HS, Alsharif DA, Elsawah WF. Heme iron polypeptide (proferrin®-ES) versus iron saccharate complex (ferrosac) for treatment of iron deficiency anemia during pregnancy. Acta Med Int 2017;4:56-61

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