Iron backed by science. Scientifically superior absorption with less side effects
Whether you are an athlete, a woman looking to maintain healthy iron levels during her cycle, or one of the many other people who are looking for a safe, effective way to support healthy iron levels, Proferrin® can help. Studies show that Proferrin® can also be effective during pregnancy3 when taken as directed by your doctor*.
Proferrin® ES is the original heme iron supplement. It contains Heme Iron Polypeptide, a natural form of iron found in meat. Compared to other forms of iron, it has 10-23x higher absorption 1, can be taken with or without food, coffee, calcium, or Vitamin C, and is not affected by PPIs*.
Proferrin® Clear is our all-natural option for those that don’t prefer tablets or color dyes. It contains the same amount of heme iron as Proferrin® ES; however, it comes in a dye-free gel capsule form rather than a tablet. It is a simple yet effective product with only four ingredients.
Proferrin® Forte was designed for those who need a little more iron and can benefit from the folic acid provided by our unique formula. It comes in a coated tablet form like Proferrin® ES but contains 1.5 mg more of heme iron than either ES or Clear, for a total of 12 mg, and it also contains 1000mcg (1667 mcg DFE) of folic acid.
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Heme Iron Content |
10.5 mg |
12 mg |
10.5 mg |
Folic Acid |
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1 mg |
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Form |
Tablet |
Tablet |
Capsule |
Smaller pill (dye-free capsule) |
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Easy-swallow coating |
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References: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
1) Nam, Tae-Sik & Shim, Ji & Kim, Byung-Ju & Rah, Young & kwang hyun, Park & Kim, Seon-Young & Mun, Eun-Gyeng & Jeong, Young-Ju & Han, Myung-Kwan & Cha, Youn-Soo & Chae, Soo-Wan & Im, Mie-Jae & Kim, Uh-Hyun. (2006). “Clinical Study on the Iron Absorption from
Heme-Iron Polypeptide and Nonheme-Iron*.” Nutritional Sciences The Korean Nutrition Society. 9. 295-300.
2) Ndegwa, Sarah, and Raymond Banks. (2007). “Heme Iron Polypeptide (Proferrin®) versus Oral and Injectable Iron Products for the Treatment of Anemia.”
3) Abdelazim IA, Abu-Faza M, Elbiaa AA, Othman HS, Alsharif DA, Elsawah WF. Heme iron polypeptide (Proferrin®-ES) versus iron saccharate complex (ferrosac) for treatment of iron deficiency anemia during pregnancy. Acta Med Int 2017;4:56-61
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Heme Iron |
(ferrous sulfate, ferrous gluconate, iron bisglycinate) |
High absorption rate |
15%-35% absorption |
Less than 5% absorption |
Can be taken with or without food |
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Absorption is not affected by vitamin C intake |
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Absorption is not blocked by calcium |
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Absorption is not blocked by coffee or tea |
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Absorption is not affected by PPIs |
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Less than a 2% chance of GI side effects (i.e. nausea, gas, constipation) |
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